deplete: implies a reduction in number or quantity and the actual or potential harm done by such a reduction: we cannot afford to ~ our natural resources.
drain: implies a gradual withdrawl and ultimate deprivation of what is necessary to a thing's existence and functioning: a series of personal tragedies ~ed him of hope.
exhaust: stresses a complete emptying or using up: a theme that can never be ~ed.
impoverish: suggests a deprivation of something essential to vigorous well-being : without the arts we would lead an ~ existence. 又如the dictator enriched himself but impoverished his people独裁者使自己富有、却使人民变得贫穷; 如poor farming practices impoverished the soil不良的耕种方式使土地变得贫瘠，如impoverished soil贫瘠的土地
bankrupt: suggests impoverishment to the point of imminent collapse: war has ~ed the nation of manpower and resources.
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