[12]screw up v.(常被动)(俚语)搞得乱七八糟;搅乱:Things are screwed up, as usual.事情跟平常一样糟。Screw up one’s courage 鼓起勇气
[Longman Dictionary of Contemporary English] someone who is screwed up has a lot of emotional problems because of bad or unhappy experiences in the past.