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人会被吓死吗?当然会

发布者: katy | 发布时间: 2010-1-27 15:48| 查看数: 1090| 评论数: 1|



A Charlotte, N.C., man was charged with first-degree murder of a 79-year-old woman whom police said he scared to death. In an attempt to elude cops after a botched bank robbery, the Associated Press reports that 20-year-old Larry Whitfield broke into and hid out in the home of Mary Parnell. Police say he didn't touch Parnell but that she died after suffering a heart attack that was triggered by terror. Can the fugitive be held responsible for the woman's death? Prosecutors said that he can under the state's so-called felony murder rule, which allows someone to be charged with murder if he or she causes another person's death while committing or fleeing from a felony crime such as robbery—even if it's unintentional.

But, medically speaking, can someone actually be frightened to death? We asked Martin A. Samuels, chairman of the neurology department at Brigham and Women's Hospital in Boston.

[An edited transcript of the interview follows. Thanks to AHCJ_Pia for the story suggestion.]

Is it possible to literally be scared to death?

Absolutely, no question about it.


Really? How does that happen?

The body has a natural protective mechanism called the fight-or-flight response, which was originally described by Walter Cannon [chairman of Harvard University's physiology department from 1906 to 1942]. If, in the wild, an animal is faced with a life-threatening situation, the autonomic (involuntary) nervous system responds by increasing heart rate, increasing blood flow to the muscles, dilating the pupils, and slowing digestion, among other things. All of this increases the chances of succeeding in a fight or running away from, say, an aggressive jaguar. This process certainly would be of help to primitive humans, but the problem, of course, is that in the modern world there is very limited advantage of the fight-or-flight response. There is a downside to revving up your nervous system like this.

How can the fight-or-flight response lead to death?

The autonomic nervous system uses the hormone adrenaline, a neurotransmitter, or chemical messenger, to send signals to various parts of the body to activate the fight-or-flight response. This chemical is toxic in large amounts; it damages the visceral (internal) organs such as the heart, lungs, liver and kidneys. It is believed that almost all sudden deaths are caused by damage to the heart. There is almost no other organ that would fail so fast as to cause sudden death. Kidney failure, liver failure, those things don't kill you suddenly.

What exactly happens in the heart when it's flooded with too much adrenaline?

Adrenaline from the nervous system lands on receptors of cardiac myocytes (heart-muscle cells), and this causes calcium channels in the membranes of those cells to open. Calcium ions rush into the heart cells and this causes the heart muscle to contract. If it's a massive overwhelming storm of adrenaline, calcium keeps pouring into the cells and the muscle just can't relax.

There is this specially adapted system of muscle and nerve tissue in the heart—the sinoatrial (SA) node, the atrioventricular node, and the Purkinje fibers—which sets the rhythm of the heart. If this system is overwhelmed with adrenaline, the heart can go into abnormal rhythms that are not compatible with life. If one of those is triggered, you will drop dead.

What is an example of one of these deadly heart rhythms?

In most cases, it's probably ventricular fibrillation that causes these sudden deaths from fear. Ventricular fibrillation basically causes the ventricles (lower chambers of the heart) to vibrate in a way that hampers their ability to deliver blood to the body.

What other emotional states besides fear could lead to these fatal heart rhythms?

Any strong positive or negative emotions such as happiness or sadness. There are people who have died in intercourse or in religious passion. There was a case of a golfer who hit a hole in one, turned to his partner and said, "I can die now"—and then he dropped dead. A study in Germany found an increase of sudden cardiac deaths on the days that the German soccer team was playing in the World Cup. For about seven days after the 9/11 terrorists attacks on the World Trade Center and Pentagon there was an increase of sudden cardiac death among New Yorkers.

Who is most likely to suffer from sudden death?

A predisposition to heart disease would probably increase your risk of sudden death, but it happens at all ages and can happen to otherwise healthy people.



夏洛特市(美国北卡罗来纳州)一名男子因被警方认为吓死一名79岁的女士而面临一级谋杀罪的指控。据美联社报道,在进行了一场拙劣的抢劫后,20岁的Larry Whitfield 为了逃避警方的追捕闯入了Mary Parnell 家中躲藏了起来。警方称虽然他没有和 Parnell 发生任何接触,但是她却因为恐惧引起心脏病的发作而造成了死亡。这名逃犯应该为这名女士的死亡负责吗?检察官称他的行为完全符合国家所谓的重罪谋杀条款,该条款规定正在犯重罪(如抢劫)的人在犯罪或逃避追捕过程中若造成了他人的死亡,即便是无意的,也可以被以谋杀罪指控。

但从医学的角度看,人真的会因为害怕而死亡吗?我们询问了波士顿布莱格姆暨妇产医院(Brigham and Women's Hospital)神经内科的主任 Martin A. Samuels 。

(以下是这次访谈的笔录,感谢 AHCJ Pia 提供的故事建议。)

人会被吓死吗?

当然可以,毫无疑问。

真的吗?这是如何发生的?

身体有一种叫做战斗或飞行反应的自然保护机制。该机制由 Walter Cannon (哈弗大学生理学系主任,1906-1942)首先报道。在野生环境中,某个动物生命遭受威胁时,植物神经系统会做出一定的反应,如心率上升、肌肉充血、微血管扩张、消化减慢等等。这些可以增加斗争中或者是逃避美洲虎追捕中成功的几率。这个过程确实对与原始人类有所帮助,但问题是在现代社会中战斗或飞行反应的优势非常的有限。你的神经系统像这样复苏,也有消极的一面。

战斗或飞行反应是如何导致死亡的?

植物神经系统应用肾上腺素(一种神经递质或者化学信使)将信号传递给身体各个部分从而激活战斗或飞行反应。大量的这种化学物质是有害的,它可以损害心、肺、肝和肾等内脏器官。可以确信的是大多数的突然死亡都是心脏衰竭造成的。几乎没有别的器官可以这样快地出现导致死亡的衰竭。肾衰竭、肺衰竭不会导致你突然的死亡。

太多的肾上腺素流经心脏时会发生什么?

来自于神经系统的肾上腺素与心肌细胞上的受体结合,从而导致细胞膜上的钙通道打开。钙离子涌入心脏细胞造成心肌收缩。如果有超大规模的肾上腺素,那么钙就会源源不断地进入细胞那么肌肉就不能够舒张。

心脏的肌肉与神经组织中有一种特殊的系统——窦房结、房室结和浦肻野纤维,他们决定了心脏的节律。如果这个系统被肾上腺素扰乱,心率就会异常,生命就会遭受影响。如果它们中的一个被触发,你就会发生猝死。

有关于这种死亡心律的例子吗?

多数情况下,最可能发生的由恐惧引发的心室颤动导致的突然死亡。心室颤动会造成心室(心脏中较小的腔)震动而阻碍它们向全身供血的能力。

除了害怕外还有什么情感会导致这种致命的心率?

任何强烈的积极或消极的情感如开心、沮丧。有人因为性交或宗教热情而死亡的。有一个高尔夫手一杆入洞,和他的搭档说:“我死而无憾了”,然后突然死了。德国一项研究发现在德国足球队在世界杯中比赛的时候,心脏问题造成死亡的人数就会上升。世贸大楼和五角大楼911恐怖袭击后大约7天中纽约心脏问题造成死亡的人数也上升了。

什么人更容易突然死亡?

心脏病的易感性可能会使你突然死亡的风险上升,但是突然死亡可以发生在各个年龄,哪怕其他方面都很健康的人也不能幸免。

最新评论

NCE1-Mary 发表于 2010-1-27 20:59:38
什么人更容易突然死亡?

心脏病的易感性可能会使你突然死亡的风险上升,但是突然死亡可以发生在各个年龄,哪怕其他方面都很健康的人也不能幸免。Who is most likely to suffer from sudden death?

A predisposition to heart disease would probably increase your risk of sudden death, but it happens at all ages and can happen to otherwise healthy people.
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